946 Does Serum Troponin I Correlate with Severity of Hypoxic Ischaemic Encephalopathy?
نویسندگان
چکیده
منابع مشابه
Cooling for newborns with hypoxic ischaemic encephalopathy.
BACKGROUND Newborn animal and human pilot studies suggest that mild hypothermia following peripartum hypoxia-ischaemia in newborn infants may reduce neurological sequelae, without adverse effects. OBJECTIVES To determine whether therapeutic hypothermia in encephalopathic asphyxiated newborn infants reduces mortality and long-term neurodevelopmental disability, without clinically important sid...
متن کاملSonographic Changes in Hypoxic-Ischaemic Encephalopathy
Hypoxic-ischaemic encephalopathy (HIE) in a full-term infant is a clinically defined syndrome of the disturbed neurologic function in the earliest days after birth in infancy, manifested by difficulty with initiating and maintaining respiration, the depression of the muscle tone and reflexes, the subnormal level of consciousness and often seizures (Nelson & Leviton, 1991). HIE is the term used ...
متن کاملTherapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy.
There is now a strong evidence base supporting therapeutic hypothermia for infants with moderate or severe neonatal hypoxic ischaemic encephalopathy. Experimental and clinical data indicate that induced hypothermia reduces cerebral hypoxic ischaemic injury and randomized clinical trials in newborns with hypoxic ischaemic encephalopathy confirm improved neurological outcomes and survival at 18 m...
متن کاملMultiorgan dysfunction in infants with post-asphyxial hypoxic-ischaemic encephalopathy.
BACKGROUND Multiorgan dysfunction (MOD) is one of four consensus based criteria for the diagnosis of intrapartum asphyxia. The theoretical concept behind MOD is the diving reflex (conservation of blood flow to vital organs at the cost of non-vital organs). OBJECTIVES To assess the patterns of involvement of each major organ/system and combinations of involvement in infants with post-asphyxial...
متن کاملTherapeutic hypothermia for hypoxic-ischaemic encephalopathy in the newborn infant.
PURPOSE OF REVIEW This review examines recent findings from experimental models and clinical trials of induced hypothermia as treatment after cerebral hypoxia-ischaemia in term newborn infants. RECENT FINDINGS Experimental hypothermia inhibits many steps in the biochemical cascade that produces severe brain injury after hypoxia-ischaemia. This is in contrast to pharmacological agents, which t...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2010
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-201011001-00946